1. Hypothalamus is the controlling centre for hypophysis.
2. Hypothalamus secretes releasing factors and inhibiting factors and hence regulate the secretions of hypophysis. E.g. Adrenocorticotropin hormone releasing factor or CRF; Thyrotropin releasing factor or TSHRF; GHRF and GHRIE i.e. Growth hormone releasing and release inhibiting factor, etc.
3. Hypothalamus forms the hypothalamohypophyseal axis through which transportation of neurohormones take place.
4. Hormones like vasopressin and oxytocin are secreted by neurosecretory cells of hypothalamus.
5. Hypothalamus can register the internal changes in the body as it is a part of diencephalon and thus it accordingly brings about coordination in the body through endocrine system.
