Question

The Atrial wall of the human heart secretes a very important peptide hormone. What is the name of that hormone?
1. ANF
2. GIP
3. CCK
4. ADH

Answer 1

Correct Answer - Option 1 : ANF

The correct answer is ANF.

• Atrial Natriuretic Peptide ( ANP ) is also known as Atrial Natriuretic Factor ( ANF ).
• It is a type of hormone that is secreted from the cardiac atria. 
• The function of ANP includes causing a reduction in expanded extracellular fluid ( ECF ) volume by increasing renal sodium excretion.
• ANP is synthesized and secreted by cardiac muscle cells in the walls of atria in the heart.
• Volume receptors are present in these cells that respond to increased stretching of the arterial wall due to increased atrial blood volume.
• De Bold in 1981 dicovered the natriuretic factor.

• The gastric inhibitory polypeptide, a hormone secreted by cells of the intestinal mucosa that blocks the secretion of hydrochloric acid into the stomach.
• Cholecystokinin (CCK) is a neuropeptide and gut hormone that regulates pancreatic enzyme secretion and gastrointestinal motility and acts as a satiety signal.
• ADH is also called arginine vasopressin, a hormone made by the hypothalamus in the brain and stored in the posterior pituitary gland. 

 

There are a total of three types of atrial natriuretic peptide receptors namely -

1. NPR1
2. NPR2
3. NPR3