There are 3 Pairs and 1 Octet that reduce as given below:
Pair-1(m0 + m4) reduces to U’W’Z’
Pair-2(m6 + m7) reduces to U’VW
Pair-3(m10 + m11) reduces to UV’W
Octet (m1 + m3 + m5 + m7 +m9 + m11 + m13 + m15) reduces to Z
Simplified Boolean expression for given K-map is F(U, V, W, Z) = U’W’Z’ + U’VW + UV’W + Z